Project Concept
Help with your project concept
- Has a similar antibody been published or raised in the past?
- Which animal species will be most suitable?
- How many animals should be immunized?
- What about a multiplex approach?
- hat could be a suitable test system?
|
(Surcharge) |
Full support |
Full support |
| Software-based Antigenicity Prediction |
Included |
Included |
Included |
Advanced Antigen Advice
Advanced Antigen Advice
- Check for sequence problems that require particular attention (high sequence conservation between different species, low antigenicity)
- Peptide versus protein antigen (Which one would be most approipriate for the respective situation?)
- Cloning strategy (Which antigen region? Which tag?)
- How to make use of inclusion bodies (protocol provided, which does not need any solubilisation)
- Peptide selection (discussion of pros and cons of individual sequence candidates)
|
(Surcharge) |
Full support |
Full support |
| Epitope Mapping (e.g. to copy a well-performing antibody) |
Option, ask for a quotation |
Option, ask for a quotation |
Option, ask for a quotation |
| Pre-selection of Pre-immune Sera? |
Yes |
Yes |
No (irrelevant if antibodies are to be affinity purified) |
| Submission & Expert Discussion of your Test Results |
(Surcharge) |
Yes, you are explicitly encouraged to do so! |
Yes, you are explicitly encouraged to do so! |
Project Modification(s)
Project Modification(s)
- Total duration of the project (What is a reasonable duration for the project you have in mind?)
- Project extension(s)
- Additional boosts
- Additional serum sampling
- Animal "parking"
|
Yes, upon your timely request (1 week in advance of changes) |
Yes, upon your short notice (4 days in advance of changes) |
Yes, even upon very short notice (1 day or same day in urgent cases) |
Decision Making
Decision Making
- What are the consequences of my test results?
- How can we confirm or improve the results?
- What about boosting and booster doses?
- What to do next?
|
You decide what to do next |
We will discuss all options with pros & cons and jointly find the best solution together with you |
We will discuss all options with pros & cons and jointly find the best solution together with you |
| Animals |
Fast growing breed with high serum yields |
Fast growing breed with high serum yields |
Special breed, selected for highest immunological responsiveness (growing slowlier) |
| Animal Husbandry |
Conventional; in accordance with German and European requirements |
Conventional; in accordance with German and European requirements |
Stress-free, "happy" animals, mostly kept in groups in ground-level enclosures with plenty of straw; outperforming any national and international legally required standards |
